Could a drug prevent depression and PTSD? | Rebecca Brachman

The path to better medicine is paved with accidental yet revolutionary discoveries. In this well-told tale of how science happens, neuroscientist Rebecca Brachman shares news of a serendipitous breakthrough treatment that may prevent mental disorders like depression and PTSD from ever developing. And listen for an unexpected — and controversial — twist.

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  • I strongly believe in this. I wish ketamine was a legal treatment for depression.

    Windley June 29, 2020 10:24 pm Reply
  • Now it makes sense, my recreational use of Special K in my later teenage years were difficult and I wondered why I wasn’t messed up for life from the experiences that some of my other friends through the year have been affected.

    Erin S. June 29, 2020 10:24 pm Reply
  • 17:59 "This could be the beginning of the end of the mental health epidemic" Amen to that

    Sid June 29, 2020 10:24 pm Reply
  • I have been asking my mental health person for years about ketamine treatments she finally told me about a doctor that gives you ketamine nasal spray treatments. Not only do I suffer from major depression but I also have idiopathic hypersomnolence without medication I can sleep for 30 hours no problem and then wake up still totally exhausted woo hoo

    Linda Napp June 29, 2020 10:24 pm Reply
  • Meanwhile, a corona virus vaccine will probably be approved half the time sooner that it's supposed to be. What I am saying is, I dont think they feel an urgency to create a treatment for depression, eventhough people are suffering incredible amounts of pain with each passing day.

    Mohammed Kortam June 29, 2020 10:24 pm Reply
  • a this lecture gave me a lot of lessons thank you

    10214한재연 June 29, 2020 10:24 pm Reply
  • This is amazing , truly incredible. We truly do have the best scientists in the world in our country.

    Noah Jenewein June 29, 2020 10:24 pm Reply
  • Excellent information. One of the best talks I've heard.

    Rebekka Dodge June 29, 2020 10:24 pm Reply
  • MDMA, psilocybin and ketamine 👌

    The Yorkshire Carper June 29, 2020 10:24 pm Reply
  • She’s wearing my pajama top

    Robin4137 June 29, 2020 10:24 pm Reply
  • everyone is deepressed , don’t be too worried so it will get worse! all you can do is enjoy your life, be kind with people living around you and always change your boring old life.stay strong anyways ❤️

    Cloudy Ann June 29, 2020 10:24 pm Reply
  • If this truly works for depression, it will never ever be available to the general public. Big pharma will never let this out. They are making too much money with anti-depressants, and it’s costing us all in terms of our well-being and our lives. So, thank you big pharma for killing us and suppressing the truth.

    Sterling Archer June 29, 2020 10:24 pm Reply
  • What about sexual dysfunction after ssri? (pssd) could ketamine help for it? Or does it make it worse

    oBluePandaO June 29, 2020 10:24 pm Reply
  • I would love to be “inappropriately happy” for a change! I pray this drug gets

    Patti Hawks June 29, 2020 10:24 pm Reply
  • I feel like this character was based on Amelia Sheppard… 🤔

    Warrior Son June 29, 2020 10:24 pm Reply
  • I took many Antidepressants for many years. Now I have PSSD because of them. Never Take these drugs! They make you impotent!

    Sir Gando June 29, 2020 10:24 pm Reply
  • My provider is administering ketamine now. My issue is that my Medicare will only pay for thd esketamine nasal med which only has a 40 percent success rate while the IV ketamine she also administers is 80 percent successful. Hmmmm makes me wonder why most insurance if any do NOT cover the IV ketamine. If I chose to do the esketamine it's 2 times per week for 4 weeks also and I would have to stay at her clinic for 2 hours after each dose to be monitored. While the IV ketamine requires ZERO time after administration to stay for observation.

    Charlotte Knutsen June 29, 2020 10:24 pm Reply
  • Excellent, time to try out Calypsol!

    Sten Andersson June 29, 2020 10:24 pm Reply
  • Why does it seem almost everyone except police get mentioned for depression or PTSD? I have read a lot and I see often that police have or are high risk for this illness. I can only imagine how hard it must be for them since they are expected to not show emotions while on duty yet see and deal with our worse nightmares. But it would be great if they can be checked because I know there is a high divorce rate as well as a high suicide rate.

    James Cowan June 29, 2020 10:24 pm Reply
  • My antidepressants help with my anxiety but not with my depression. I also suffer from ptsd and I really want to try ketamine treatment.

    Melanie Mathews June 29, 2020 10:24 pm Reply
  • Too bad ketamine treatments cost thousands of dollars…

    surlykaratemonkey June 29, 2020 10:24 pm Reply
  • I recently started ketamine for mental health and it has changed my LIFE. This talk was very well articulated thank you

    rez June 29, 2020 10:24 pm Reply
  • Thank you for doing what you do.

    Nelson Santiago June 29, 2020 10:24 pm Reply
  • This girl pretends she discovered murine stress models of mice and the effect of ketamine. How incredibly dishonest. TED should delete this fraud.

    John E June 29, 2020 10:24 pm Reply
  • Talking about Ketamine starts at 8:00. FF to that

    Matthew00049 June 29, 2020 10:24 pm Reply
  • By way of sad irony, this popped up after an Irving Kirsch video explaining the myths and dangers of largely ineffectual but dangerous anti-depressants. This lady moved from cures for real diseases like TB to curative claims in respect of depression. The correlation is dubious.

    David Drew June 29, 2020 10:24 pm Reply
  • NO NO NO, Ive worked with PTSD for over 10 years drugs don't work end of. Talking based therapies work

    New Leaf Programme June 29, 2020 10:24 pm Reply
  • I was completely on board until I heard it was just Special K. I have met a lot of people with severe depression that have tried special K over the years and they still have depression. Could it be that it only works if your depression was about to come on for the first time and the special K would allow the body to handle the stress and thus never get the depression in the first place? Because if so that would mean that the drug would have no help for all the people who already have depression right?

    Bryan Black June 29, 2020 10:24 pm Reply
  • why do these talks so long. They like the sound of there own voice

    david jones June 29, 2020 10:24 pm Reply
  • PLEASE do whatever it takes to make this medication available to the public. I'll simply say that my life depends on it. I'm not able to do 90% of the things I want in life I just cant do. I hope someone hears me. Thank you for your work to help people in my condition.

    Joel Zimmerman June 29, 2020 10:24 pm Reply
  • They used Ketamine via IV on me three separate times in the ER for severe migraine pain and compared to most options it was fairly effective.
    You have to keep in mind that by the time the pain is severe enough to take me to the ER my options are somewhat limited as the pain and other symptoms are so far out of control.
    I’ve been considering investigating it to combat my major depression now.
    As for my share of pain; I think I’ve given enough.

    Kimberly Rice June 29, 2020 10:24 pm Reply
  • Male depression: I wana die.
    Female depression: my lifes so hard my waistline is so big cus i eat to much.

    HomelessMan InKorea June 29, 2020 10:24 pm Reply
  • 2017: A person is discussing about drug that could prevent depression and PTSD

    2019: The same person is still discussing about drug that could prevent depression and PTSD.

    What changed?

    FoodLover FoodHater June 29, 2020 10:24 pm Reply
  • My mom works at a place where they help people get past drugs like a recovery center, and she said Ketamine was a super addictive drug that people were in there for. I have bad anxiety but I’m not going that long 40 year path of ongoing drug addiction and crime for my stupid 15 year old choice wanting to cure my anxiety to socialize more with the world at that time when I can just grow out of it when I’m 16

    Bang June 29, 2020 10:24 pm Reply
  • Its all food dairy and gluten inflammation in your brain

    matthew gonano June 29, 2020 10:24 pm Reply
  • Ketamine is a dissociative. If you microdose on Ketamine obviously it’ll “help you get through tough times.”

    Also when will the pharmaceutical industry be held accountable for SSRIs which DO NOT WORK. They act by diminishing frontal lobe activity and suppressing emotions. Often times they either make people feel numb or occasionally frontal lobe activity becomes so diminished that people commit horrific crimes they normally wouldn’t do. This is backed up science. In 50 years I would not be surprised if they considered antidepressants the equivalent of blood letting. It’s so stupid.

    If psilosibyn and LSD are found to help people than hoorah! BUT DO NOT GET AHEAD OF YOURSELVES FOLKS the brain is extremely complicated. If I find out those drugs are put on the market with as few studies as Marijjuana which is ALSO not a godsend folks —(the most recent study says risk of psychosis increase by 3x! With just 10 mg). Cmon people. We desperately want LSD, and hallucinogens and other dissociatives to become legalized for no other reason so we can legally trip. We need to stop with this bullshit and study each drug, their method of action, and how they work for a significant number. I think we need a meta analysis, we need a huge 20000 plus study along with placebo and control group. We need long term effects. We need to know everything.

    Alex Al June 29, 2020 10:24 pm Reply
  • Poor people insurance doesn’t cover expensive new drugs only meant for the wealthy and privileged….nice TED talk….for the wealthy and privileged

    Dan Woods June 29, 2020 10:24 pm Reply
  • And will it only be affordable to the wealthy and privileged…..I’m a veteran with depression and ptsd and Medicare….will insurance cover new drugs…nope….

    Dan Woods June 29, 2020 10:24 pm Reply
  • I expected to see a lot of just smoke weed comments, I'm glad I don't. Those are the worst type of stoners

    Blaggard999-_- June 29, 2020 10:24 pm Reply
  • She should read Irving Kirsch. I’m not kidding, all of this is wrong… And it’s actually a good thing it is

    12345sebster June 29, 2020 10:24 pm Reply
  • Thank you! This helped me understand how self medicating k helped me get out of my depression. I hope ppl in the near future gets to take it with a therapist in a better way then I did it.
    Bless 🙏😌

    Johan Magnusson June 29, 2020 10:24 pm Reply
  • Yay! Amazing treatment discovered. Can I have some? No. 🙁

    John S June 29, 2020 10:24 pm Reply
  • What an AMAZING TED regardless of personal opinions (I’m wise therefore haven’t made my own yet) on the subject!!! Awesome job!!! 👏🏻👏🏻👏🏻👏🏻

    Liu Bliu June 29, 2020 10:24 pm Reply
  • Yeah, next month I'll just ask my psychiatrist to prescribe ketamine to prevent my borderline personality disorder, a trauma-induced mental condition, from getting worse! Thanks for waiting until 15.55 to drop THAT little bombshell!

    People bent on drug abuse have, yet again, derailed mental health treatment by making drugs that could actually HELP people virtually impossible to get legally.

    Anybody else know that MMDA, or "Ecstasy", "E", or "Vitamin E", as clubbers call it, worked virtual miracles with people with attachment disorder and has even CURED people with PTSD? But some irresponsible research subject nvolved with early scientific studies took some to a party, and the rest is history.

    I might be helped with, or even cured of, multiple psychiatric issues by the responsible, therapeutic use of these drugs, but even if I were willing to move to Santa Cruz CA, I'm not sure MAPS (Multidisciplinary Association of Psychedelic Studies) would allow me to participate in any studies with either drug, or with marijuana, all of which they have government approval to administer, because I'm over 50 years old and both mental and physical issues are chronic. Anyone who thinks they may have better odds would do well to visit, read about what they've done and are doing, and maybe fire off an email. I'm writing one now, an uncharacteristically optimistic gesture.

    Tamara Jessup June 29, 2020 10:24 pm Reply
  • CBD oil is an all natural way to treat depression and PTSD. No man made pills. No bad side effects. For more information go to

    Ashley Hundley June 29, 2020 10:24 pm Reply
  • Ketamine drips are very expensive, insurance coverage is not available. I was offered to try it however, I declined. It lasts a week to two then you have to go back and get another
    Ketamine drip { they play music as you lay back in a cushioned chair in the dark } as it takes 20 minutes. Sometimes it doesn't even work, unfortunately you still get charged. It is
    just too expensive for me $275 – $350 every two weeks.

    Eleni Eliades June 29, 2020 10:24 pm Reply

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